Download Affective and Schizoaffective Disorders: Similarities and by A. Marneros, M. T. Tsuang (auth.), Professor Dr. med. PDF

By A. Marneros, M. T. Tsuang (auth.), Professor Dr. med. Andreas Marneros, Ming T. Tsuang M.D., Ph.D., D.Sc. (eds.)

Several contributions in our first ebook approximately schizo affective problems (Marneros and Tsuang, Schizoaffective Psychoses, Springer-Verlag, 1986) supported the belief that schizoaffective issues vary in proper methods from schizophrenic issues. The category of schizo affective problems as a subgroup of schizophrenia has additionally been criticized, and empirical learn in medical, genetic, healing, and prognostic parts helps the concept there are a few powerful similari­ ties among schizo affective and affective issues. in fact, there aren't purely similarities among those teams, but in addition transformations simply as there are among schizo affective and schizophrenic issues. it truly is exactly the lifestyles of similarities and ameliorations among schizo affective problems and the opposite so-called standard psychological issues, i.e., schizophrenia and affective problems, which makes them a problem in psychiatric learn, a problem to the normal dichotomy within the type of issues which originated with Kraepelin. This problem is definitely proving fruitful in psychiatric examine. those "cases in among" may show that sep­ arating, dividing, and proscribing isn't continually significant. occasionally it may be extra significant to unify; to unify within the feel of establishing bridges among general teams. it truly is right here that the idea of a "psychotic continuum" can turn into proper, and the research of schizoaffective problems is of best value in study on a potential continuum of psychosis.

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Finally, a stepwise multiple regression analysis was carried out for the prediction of each of the six criteria for course and outcome by optimal combinations of variables from the set of 16 potential predictors. Expectations It was expected that schizophrenics would exhibit the highest frequencies in the categories of predictors as well as course and outcome criteria reflecting an 1 Male sex 2 Young age 3 Difficulties at work (including housework) 4 Lack of social adaptability 5 Lack of constant partnership during the last 6 months 6 Insidious onset of disease 7 Chronic course until admission 8 Chronic abuse of alcohol and/or other drugs 9 Insidious onset of the index episode 10 ScS at admission above median of total group 11 AfS at admission above median of total group 12 Sc~ at discharge above median of total group 13 AfS at discharge above median of total group 14 Bad psychopathological state at discharge (global rating) Predictors No.

They fit the concept of "endogenous" depression best of all. The group with no psychotic symptoms probably contains a mixture of some neurotic depressives and some endogenous depressives, and it is entirely possible that the groups of acute onset incongruent psychotic manics and depressives contain a small number of schizophrenics. On a practical basis, these illnesses are all similar. They respond to treatment well and they have the same quality of follow-up. Of course, as was noted earlier, the diagnosis of schizo affective disorder depends on the criteria.

S. Hospital >4 wks. S. Age first ill. S. S. S. are the more severely ill group. Response to treatment is no different among the three groups. Patients in the three groups were equally likely to respond to ECT and antidepressant medication. Of course, the mood-incongruent psychotic group was more likely to have antipsychotic drug maintenance, something which is expected. Duration of follow-up was equal among the groups, and there was no significant difference in the number of patients who relapsed.

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