By David Schiff, Santosh Kesari, Patrick C. Y. Wen
Neuro-oncology has advanced considerably as a scientific and learn self-discipline during the last few many years. Cancer Neurology in scientific perform: Neurologic problems of melanoma and its therapy, moment Edition presents clinicians from a variety of backgrounds and degrees of educating with a connection with aid concentration the differential prognosis, therapy process, and administration plan for the melanoma sufferer with neurologic indicators and findings.
The quantity starts off with an outline of the sector of neuro-oncology and a evaluation of the function of neuroimaging within the analysis of neuro-oncologic disorder. a number of chapters on interpretation and administration of universal neuro-oncologic indicators stick to. next sections include chapters at the direct and oblique neurologic issues of melanoma in addition to issues of remedy. the ultimate part specializes in the spectrum and administration of neurologic sickness in sufferers with melanoma of particular organs.
Cancer Neurology in scientific perform: Neurologic issues of melanoma and its remedy, moment Edition is a vital new paintings that goals to increase and deepen the familiarity of clinicians with the diversity and administration of neuro-oncologic illnesses so that it will enhance the standard of take care of melanoma patients.
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Extra resources for Cancer Neurology in Clinical Practice; Neurologic Complications of Cancer and Its Treatment
Also, the peritumoral mean diffusivity (MD) of metastatic lesions measured significantly greater than that of gliomas (33,35). Displacement of subcortical white matter fibers by subjective visual assessment of diffusion tensor tractography images (as opposed to tract disruption or invasion), is also more commonly seen in metastases compared to high-grade gliomas (34). Diffusion anisotropy is highly sensitive to microstructural changes that do not appear on conventional imaging. This high sensitivity is accompanied by relatively low specificity such that useful DTI-based tissue characterization may ultimately require the use of more sophisticated approaches.
Plain X-rays may be useful for identifying vertebral body metastases. Abnormalities include erosion of a pedicle and collapse of the vertebral body. Plain X-rays are suggestive of epidural extension in the presence of greater than 50% vertebral body collapse or pedicle erosion. CT scans are more sensitive than plain X-rays or bone scans for identifying vertebral metastases, and like MRI, can image paravertebral disease. MRI has replaced myelography as the definitive radiographic test for epidural metastases.
Bukte Y, Paksoy Y, Genc E et al. Role of diffusion-weighted MR in differential diagnosis of intracranial cystic lesions. Clin Radiol 2005;60(3):375–383. 30 Part II / Diagnostic Studies 33. Lu S, Ahn D, Johnson G, Cha S. Peritumoral diffusion tensor imaging of high-grade gliomas and metastatic brain tumors. AJNR Am J Neuroradiol 2003;24(5):937–941. 34. Tsuchiya K, Fujikawa A, Nakajima M et al. Differentiation between solitary brain metastasis and high-grade glioma by diffusion tensor imaging. Br J Radiol 2005;78(930):533–537.