Download Ebola and Marburg Virus by Tara C. Smith PDF

By Tara C. Smith

Ebola virus and Marburg virus are similar viruses that reason hemorrhagic fevers health problems marked through critical bleeding, organ failure, and, in lots of situations, dying. those viruses are local to Africa, the place sporadic outbreaks have happened for many years. Ebola and Marburg Virus, moment variation takes a glance on the nature and origins of those viruses, transmission, therapy, and present vaccine study. Chapters contain: a latest Plague The Emergence of Marburg Virus Ebola in Africa and past features of Filoviruses Ecology of the Viruses Detection and remedy constructing a Vaccine different Hemorrhagic Fevers.

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In a hospital setting, the reuse of unsterilized needles and syringes and the lack of barrier nursing procedures (such as masks, gowns, and gloves) were important factors in the spread of disease. Family members became infected due to close contact via bare skin, either in a hospital or a home setting. Family members often became 41 42 EBOLA AND MARBURG VIRUSES infected while preparing the corpse of an infected loved one, as cultural traditions in Africa require the ritual cleansing of the body of relatives.

Their genetic material—the material that makes up their genes—is composed of ribonucleic acid. Their genomes (the entire amount of RNA) are fairly small. Each only contains approximately 19,000 base pairs (in comparison, the human genome contains approximately 3 billion base pairs), which encode a mere 7 proteins. 1). The viruses generally appear in a long, filamentous form, but they can also be U-shaped, in the shape of a “6” (the “shepherd’s crook” appearance), or even circular. Sequence analysis shows the viruses to be most closely related to the paramyxoviruses, which include the viruses that cause such common diseases as measles and mumps.

The intensity of color correlates to the amount of antibody that is present in the serum. The darker the color, the higher the level of antibody present. ELISA is more sensitive and specific than IFA, but because a special reader is necessary to determine the results, it is a more difficult test to carry out in the field. These tests can also be used to distinguish between a current or very recent infection and a past infection. The human body produces several different types of antibodies (technically called immunoglobulins, abbreviated Ig).

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