Download Endovascular Surgical Neuroradiology: Theory and Clinical by Charles J. Prestigiacomo, Bernard R Bendok PDF

By Charles J. Prestigiacomo, Bernard R Bendok

Covering not just the newest ideas but in addition the technological know-how and purpose in the back of neuroendovascular remedy, this reference displays the present wisdom base of the endovascular surgical neuroradiology subspecialty. It covers all elements of neuroendovascular surgical procedure, similar to the technology of vascular biology to the extra complicated scientific functions in acute stroke interventions and AVMs. Written through neurologists, neurosurgeons, and neuroradiologists, this well timed textual content presents readers with a radical assessment of the entire concerns pertinent to the endovascular remedy of illnesses of the cerebrovascular process, backbone, head, and neck.

Key Features:

  • Technique chapters contain trouble avoidance and management
  • High-quality, special illustrations and up to date pictures consultant the reader via scientific innovations and technically hard procedures
  • Covers themes which are frequently ignored yet are serious to knowing the dynamics of endovascular remedy, comparable to using anticoagulants or procoagulants and the biophysics of vascular disease
  • Each bankruptcy ends with a precis which distills and highlights the major takeaways for that subject

Endovascular Surgical Neuroradiology is a key source that trainees in addition to extra pro clinicians will discuss with time and again over the process their careers.

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Extra resources for Endovascular Surgical Neuroradiology: Theory and Clinical Practice

Example text

Technical improvements, along with better understanding of the coagulation systems, have led to improved and more accessible coagulation assays that might play a key role intraoperatively. These tests include thromboelastometry, thrombin generation assay, and point-of-care platelet function aggregation assays. • As more hemostatic interventions are becoming available, such as concentrates of recombinant factors, cryoprecipitate, and fresh frozen plasma, a validated and accessible coagulation monitor assay becomes a necessity in managing patients with hemostatic disorders.

Although protein S serves as a cofactor to APC for the cleavage of factor Va and factor VIIIa, there is evidence that it can perform anticoagulatory functions independent of APC. 109 Protein S holds much clinical significance in renal nephrotic syndromes, where it is lost in the urine, leading to a hypercoagulable state. 2). 110 TAFI cleaves the C-terminal lysine residue on fibrin, essential for catalysis of plasmin activation, from the partially degraded fibrin clot. 119 α2-AP also effectively reduces the available catalytic surface for plasminogen activation by binding to fibrinogen.

Roman numerals are used to refer to the numbering of the anticoagulation factors. a, activated state of the anticoagulation factors. Coagulation Cascade 13 14 Part I General Endovascular Tenets XII XIIa XI XIa IX Tissue Factor IXa VII TFPI VIIIa APC VIIa X Xa X Antithrombin III Va Prothrombin (II) Thrombin (IIa) Fibrinogen Fibrin XIIIa Cross-linked clot Fig. 4 The coagulation cascade showing the role of the principal anticoagulants. Roman numerals are used to refer to the numbering of the anticoagulation factors.

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